Which game speed, passing ass. settings or patch are you using? How many goals did scored/concede your last season when you won the league? How do you attack against overpowered AI intercepting balls and pushing you off like crazy? What is your main weapon of scoring? Do you use R2 a lot, super cancel, a lot of crosses? Anything? I am not really a complete dummy since I was able to make it through the hard times in D2 always on professional, but how do you do it??

Thanks.
Ok, I'm glad to help. Passing assistance is 1, sometimes 2. Semi-assisted cursor change, patch 1.02 with no option file, so no gameplay file for me.
Formation is a 4-2-3-1, two DMF's, two wingers, one AMF and a striker. Sliders:
Player support - 13 for away games, 16 for home games against lesser teams, 13 for big matches
Support Range - 10
Pressing - 10
Defensive line - 10 for teams playing quick counter, 12 for long ball
Width - 13
I scored around 60-70 goals, conceded between 30 and 40, cant remember now. Cant say I had a recipe for scoring goals but my tip is do everything you can in order to maximise your chances. If you have someone with a good long rang shot, take your chances. Make a few crosses for your tall forward or try through balls for your quick forwards. Unleash everything you can and it will pay off eventually.
Try playing according to your squad strenghts and attack a lot from the wings (overlapping your fullbacks works wonders). Counter-attacking is less effective, but it still works and you can create quite a few opportunities with it. As for dribbling, yes, try R2 and assign some useful tricks to L1 + direction (just one for each direction).
If you're playing with a tall forward, press O only once. With someone quicker and smaller, low crosses are your best friends. Clever dribbling also helps, be creative instead of being a one-trick pony and most importantly, play with the mentality that you're going to win. How and when it's up to you, but the more afraid to concede goals and lose you are, worse the results.
Just an update on my situation - 1st placed on Ligue 1 with 72 points. Lyon are 2nd placed on 71 and I missed a golden opportunity to go the distance. Drew my derby match with Olympique Marseille, 1-1, they lost their match against Dijon but I couldnt capitalize. Facing Barcelona on CL quarter-finals, god help OGC Nice.