I think the response times have improved from the demo but there is a few niggling things for me:
The animations in general are extremely poor, as in - unfinished poor. Sometimes, with certain turns etc there is obviously animations missing-
The graohics also, admittedly are probably the best we have had from a pes game, but they arent as good as the hype, faces are good on certain players, dreadful on others, the crowds dont look good either
The physics are not right, i dont care what people say, they just arent... Throw a ball out with the keeper and sometimes the ball - 'jumps' out of the keepers glove...
Also there is no way that a player can kick a ball long and make the trajectory that the players on pes an make.
The online is not good, the lag varies from good to terrible - although now you can make sure before you play someone that the connection is good, it still doesnt solve the problem
The keepers arent that good either - played an online game earlier and won with a pea roller at the keeper from lucas that the keeper just parried into his own net in the last minute. Good for me

but must of been infuriating for the other guy.
The masters league is going to be the main thing for me (unless online improves a lot) and it seems better, more realistic world if you catch my drift.
Oh btw the sound (apart from the music) has got to be some of the worst in a sports game ever... Get rid of lawrenson please!!! he sounds like he is reading off a peice of paper and has the charisma of a wet sandwich.