I know injuries aren't looking good at the mo, but I'd still back you for the league. You can work around the Essien one (and given how good he is at all other things, maybe he recovers faster too!) and Drogba has barely played this season yet you've been doing pretty well. The new system relies less on him than the old (which actually relied on him about 90% of the time). Now that you have the wingers actually getting forward and involved, Anekla should be able to do the job IMO.
If you've lost Terry and Carvalho that's big, but neither will be out for long I'm led to believe. Once they're back, you have a team that can be almost guaranteed not to lose, which is a great starting point for some Franky specials.
Plus if you look at other squads, Arsenal are 2 injuries away from mediocrity (pretty much any 2 of their first XI), United are already pretty f*cked with injuries themselves (Carrick, Hargo, Scholes, maybe Rooney) and Liverpool have so far managed not to get a single one of note. If anything happens to Torres, pool are absolutely f*cked IMO. And despite his age, I can't imagine he'll play every game this season.