Try playing with 4 defenders and make all of them CB's (in stead of LB,CB,CB,RB) - Your full backs can still have attacking arrows, but the role change will make them less vulnerable to wing attacks. You need 4 decent CB's to do this. There's not much point in doing this on your right back with Zambrotta or Belletti, but it will work well with Thuram or Puyol. Also, to spread it out, someone needs to be either RM or RW (same in left side of course)
I play 4CBs and a DM, they kinda make it out for a defence. Then I play 2 AM, 2 WG and a lone striker/Target man with defensive duties and backward arrow to make it up for an attack. Under pressure this feels like 4-5-1 with good Counter Attack options. When in control you are playing an attacking 4-3-3, and with the AM's running forward, you have something like 4-1-5.
But hey, in general you need to make a formation that suits the team and not the other way round. Perhaps I use 2 wingers and a target man and your team has noone who can play WG and all possible forwards are 1.66 meters tall.